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Write My Essay For MeWeek 10 Assignment 2
Final Exam
1. Question
:
The drug recommended as primary prevention of osteoporosis
in men over seventy years is:
Alendronate (Fosamax)
Ibandronate (Boniva)
Calcium carbonate
Raloxifene (Evista)
Question 2. Question
:
Alterations in drug metabolism among Asians may lead to:
Slower metabolism of antidepressants,
requiring lower doses
Faster metabolism of neuroleptics, requiring
higher doses
Altered metabolism of omeprazole, requiring
higher doses
Slower metabolism of alcohol, requiring higher
doses
Question 3. Question
:
Some research supports that testosterone replacement therapy
may be indicated in which of the following diagnoses in men?
Age-related decrease in cognitive functioning
Metabolic syndrome
Decreased muscle mass in aging men
All of the above
Question 4. Question
:
The chemicals that promote the spread of pain locally
include _________.
serotonin
norepinephrine
enkephalin
neurokinin A
Question 5. Question
:
The DEA:
Registers manufacturers and prescribes
controlled substances
Regulates NP prescribing at the state level
Sanctions providers who prescribe drugs
off-label
Provides prescribers with a number they can
use for insurance billing
Question 6. Question
:
The trial period to determine effective anti-inflammatory
activity when starting a patient on aspirin for RA is _____.
forty-eight hours
four to six days
four weeks
two months
Question 7. Question
:
The route of excretion of a volatile drug will likely be:
The kidneys
The lungs
The bile and feces
The skin
Question 8. Question
:
Compelling indications for an ACE inhibitor as treatment for
hypertension based on clinical trials include:
Pregnancy
Renal parenchymal disease
Stable angina
Dyslipidemia
Question 9. Question
:
The American Diabetic Association has recommended which of
the following tests for ongoing management of diabetes?
Fasting blood glucose
Hemoglobin A1c
Thyroid function tests
Electrocardiograms
Question 10. Question
:
The angiotensin converting enzyme (ACE) inhibitor lisinopril
is a known teratogen. Teratogens cause Type ____ ADR.
A
B
C
D
Question 11. Question
:
The goals of therapy when prescribing HRT include reducing:
Cardiovascular risk
Risk of stroke or other thromboembolic event
Breast cancer risk
Vasomotor symptoms
Question 12. Question
:
Patients who have angina, regardless of class, who are also
diabetic should be on:
Nitrates
Beta blockers
ACE inhibitors
Calcium channel blockers
Question 13. Question
:
The New York Heart Association and the Canadian
Cardiovascular Society have described grading criteria for levels of angina.
Angina that occurs with unusually strenuous activity or on walking or climbing
stair after meals is:
Class I
Class II
Class III
Class IV
Question 14. Question
:
Patients with allergic rhinitis may benefit from a
prescription of:
Fluticasone (Flonase)
Cetirizine (Zyrtec)
OTC cromolyn nasal spray (Nasalcrom)
Any of the above
Question 15. Question
:
Kyle has Crohn’s disease and has a documented folate
deficiency. Drug therapy for folate deficiency anemia is:
Oral folic acid 1 to 2 mg/day
Oral folic acid 1 gm/day
IM folate weekly for at least six months
Oral folic acid 400 mcg daily
Question 16. Question
:
The treatment for vitamin B12 deficiency is:
1,000 mcg daily of oral cobalamin
2 gm/day of oral cobalamin
100 mcg/day vitamin B12 IM
500 mcg/dose nasal cyanocobalamin two sprays
once a week
Question 17. Question
:
Nonadherence is especially common in drugs that treat
asymptomatic conditions, such as hypertension. One way to reduce the likelihood
of nonadherence to these drugs is to prescribe a drug that:
Has a short half-life so that missing one dose
has limited effect
Requires several dosage titrations so that
missed doses can be replaced with lower doses to keep costs down
Has a tolerability profile with less of the
adverse effects that are considered “irritating,” such as nausea and dizziness
Must be taken no more than twice a day
Question 18. Question
:
Type II diabetes is a complex disorder involving:
Absence of insulin production by the beta
cells
A suboptimal response of insulin-sensitive
tissues in the liver
Increased levels of GLP in the postprandial
period
Too much fat uptake in the intestine
Question 19. Question
:
Metformin is a primary choice of drug to treat hyperglycemia
in type II diabetes because it:
Substitutes for insulin usually secreted by
the pancreas
Decreases glycogenolysis by the liver
Increases the release of insulin from beta
cells
Decreases peripheral glucose utilization
Question 20. Question
:
Gender differences between men and women in pharmacokinetics
include:
More rapid gastric emptying so that drugs
absorbed in the stomach have less exposure to absorption sites
Higher proportion of body fat so that
lipophilic drugs have relatively greater volumes of distribution
Increased levels of bile acids so that drugs
metabolized in the intestine have higher concentrations
Slower organ blood flow rates so that drugs
tend to take longer to be excreted
Question 21. Question
:
If not chosen as the first drug in hypertension treatment,
which drug class should be added as the second step because it will enhance the
effects of most other agents?
ACE inhibitors
Beta blockers
Calcium channel blockers
Diuretics
Question 22. Question
:
A nineteen-year-old male was started on risperidone.
Monitoring for risperidone includes observing for common side effects,
including:
Bradykinesia, akathisia, and agitation
Excessive weight gain
Hypertension
Potentially fatal agranulocytosis
Question 23. Question
:
Levetiracetam has known drug interactions with:
Oral contraceptives
Carbamazepine
Warfarin
Few, if any, drugs
Question 24. Question
:
When the total daily insulin dose is split and given twice
daily, which of the following rules may be followed?
Give two-thirds of the total dose in the
morning and one-third in the evening.
Give 0.3 units/kg of premixed 70/30 insulin,
with one-third in the morning and two-thirds in the evening.
Give 50% of an insulin glargine dose in the
morning and 50% in the evening.
Give long-acting insulin in the morning and
short-acting insulin at bedtime.
Question 25. Question
:
Which of the following factors may adversely affect a
patient’s adherence to a therapeutic drug regimen?
Complexity of the drug regimen
Patient’s perception of the potential adverse
effects of the drugs
Both A and B
Neither A nor B
Question 26. Question
:
The time required for the amount of drug in the body to
decrease by 50% is called:
Steady state
Half-life
Phase II metabolism
Reduced bioavailability time
Question 27. Question
:
Drugs that are absolutely contraindicated in lactating women
include:
Selective serotonin reuptake inhibitors
Antiepileptic drugs such as carbamazepine
Antineoplastic drugs such as methotrexate
All of the above
Question 28. Question
:
Tobie presents to clinic with moderate acne. He has been
using OTC benzoyl peroxide at home with minimal improvement. A topical
antibiotic (clindamycin) and a topical retinoid adapalene (Differin) are
prescribed. Education of Tobie would include which one of the following
instructions?
He should see an improvement in his acne
within the first two weeks of treatment.
If there is no response in a week, he should
double the daily application of adapalene (Differin).
He may see an initial worsening of his acne
that will improve in six to eight weeks.
Adapalene may cause bleaching of clothing.
Question 29. Question
:
Martin is a sixty-year-old with hypertension. The first-line
decongestant to be prescribed would be:
Oral pseudoephedrine
Oral phenylephrine
Nasal oxymetazoline
Nasal azelastine
Question 30. Question
:
A woman who is pregnant and has hyperthyroidism is best
managed by a specialty team that will most likely treat her with:
Methimazole.
Propylthiouracil.
Radioactive iodine.
Nothing; treatment is best delayed until after
her pregnancy ends.
Question 31. Question
:
A twenty-four-year-old male received multiple fractures in a
motor vehicle accident that required significant amounts of opioid medication
to treat his pain. He is at risk for Type __ ADR when he no longer requires the
opioids.
A
C
E
G
Question 32. Question
:
Second-generation antihistamines such as loratadine
(Claritin) are prescribed for seasonal allergies because they:
Are more effective than first-generation
antihistamines
Are less sedating than first-generation
antihistamines
Are prescription products and, therefore, are
covered by insurance
Can be taken with CNS sedatives, such as
alcohol
Question 33. Question
:
Steady state is:
The point on the drug concentration curve when
absorption exceeds excretion
When the amount of drug in the body remains
constant
When the amount of drug in the body stays
below the minimum toxic concentration (MTC)
All of the above
Question 34. Question
:
Jayla is a nine-year-old who has been diagnosed with
migraines for almost two years. She is missing up to a week of school each
month. Her headache diary confirms she averages four or five migraines per
month. Which of the following would be appropriate?
Prescribe amitriptyline (Elavil) daily, start
at a low dose and increase the dose slowly every two weeks until effective in
eliminating migraines.
Encourage her mother to give her Excedrin
Migraine (aspirin, acetaminophen, and caffeine) at the first sign of a headache
to abort the headache.
Prescribe propranolol (Inderal) to be taken
daily for at least three months.
Explain that it is rare for a nine-year-old to
get migraines and that she needs an MRI to rule out a brain tumor.
Question 35. Question
:
Josie is a five-year-old who presents to the clinic with a
forty-eight-hour history of nausea, vomiting, and some diarrhea. She is unable
to keep fluids down, and her weight is 4 pounds less than her last recorded
weight. Besides intravenous (IV) fluids, her exam warrants the use of an
antinausea medication. Which of the following would be the appropriate drug to
order for Josie?
Prochlorperazine (Compazine)
Meclizine (Antivert)
Promethazine (Phenergan)
Ondansetron (Zofran)
Question 36. Question
:
Long-term use of PPIs may lead to:
Hip fractures in at-risk persons
Vitamin B6 deficiency
Liver cancer
All of the above
Question 37. Question
:
Many patients self-medicate with antacids. Which patients
should be counseled to not take calcium carbonate antacids without discussing
with their providers or a pharmacist first?
Patients with kidney stones
Pregnant patients
Patients with heartburn
IN Postmenopausal women
0
of 2.5
Question 38. Question
:
Beta blockers treat hypertension because they:
Reduce peripheral resistance.
Vasoconstrict coronary arteries.
Reduce norepinephrine.
Reduce angiotensin II production.
Question 39. Question
:
Precautions that should be taken when prescribing controlled
substances include:
Faxing the prescription for a Schedule II drug
directly to the pharmacy
Using tamper-proof papers for all
prescriptions written for controlled drugs
Keeping any presigned prescription pads in a
locked drawer in the clinic
Using only numbers to indicate the amount of
drug to be prescribed
Question 40. Question
:
The tricyclic antidepressants should be prescribed
cautiously in patients with:
Eczema
Asthma
Diabetes
Heart disease
Question 41. Question
:
An ACE inhibitor and what other class of drug may reduce proteinuria
in patients with diabetes better than either drug alone?
Beta blockers
Diuretics
Nondihydropyridine calcium channel blockers
Angiotensin II receptor blockers
Question 42. Question
:
Metoclopramide improves GERD symptoms by:
Reducing acid secretion
Increasing gastric pH
Increasing lower esophageal tone
Decreasing lower esophageal tone
Question 43. Question
:
Patient education regarding prescribed medication includes:
Instructions written at the high school
reading level
Discussion of expected ADRs
How to store leftover medication such as
antibiotics
Verbal instructions always in English
Question 44. Question
:
If a patient with H. pylori positive PUD fails first-line
therapy, the second-line treatment is:
A PPI BID plus metronidazole plus tetracycline
plus bismuth subsalicylate for fourteen days
Testing H. pylori for resistance to common
treatment regimens
A PPI plus clarithromycin plus amoxicillin for
fourteen days
A PPI and levofloxacin for fourteen days
Question 45. Question
:
A patient with a COPD exacerbation may require:
Doubling of inhaled corticosteroid dose
Systemic corticosteroid burst
Continuous inhaled beta 2 agonists
Leukotriene therapy
Question 46. Question
:
Angela is a black woman who has heard that women of African
descent do not need to worry about osteoporosis. What education would you
provide Angela about her risk?
She is ; black women do not have much risk of
developing osteoporosis due to their dark skin.
Black women are at risk of developing
osteoporosis due to their lower calcium intake as a group.
If she doesn’t drink alcohol, her risk of
developing osteoporosis is low.
If she has not lost more than 10% of her
weight lately, her risk is low.
Question 47. Question
:
The role of the nurse practitioner in the use of herbal
medication is to:
Maintain competence in the prescribing of
common herbal remedies.
Recommend common OTC herbs to patients.
Educate patients and guide them to appropriate
sources of care.
Encourage patients to not use herbal therapy
due to the documented dangers.
Question 48. Question
:
Ray has been diagnosed with hypertension, and an ACE
inhibitor is determined to be needed. Prior to prescribing this drug, the nurse
practitioner should assess for:
Hypokalemia
Impotence
Decreased renal function
Inability to concentrate
Question 49. Question
:
Long-acting beta-agonists received a black box warning from
the US Food and Drug Administration due to the:
Risk of life-threatening dermatological
reactions
Increased incidence of cardiac events when
long-acting beta-agonists are used
Increased risk of asthma-related deaths when
long-acting beta-agonists are used
Risk for life-threatening alterations in
electrolytes
Question 50. Question
:
Off-Label prescribing is:
Regulated by the FDA
Illegal by NPs in all states (provinces)
Legal if there is scientific evidence for the
use
Regulated by the DEA
Question 51. Question
:
Adam has type I diabetes and plays tennis for his
university. He exhibits knowledge deficit about his insulin and his diagnosis.
He should be taught that:
He should increase his increase his
carbohydrate intake during times of exercise intake during times of exercise.
Each brand of insulin is equal in
bioavailability, so buy the least expensive.
Alcohol produces hypoglycemia and can help
control his diabetes when taken in small amounts.
If he does not want to learn to give himself
injections, he may substitute an oral hypoglycemic to control his diabetes.
Question 52. Question
:
Prior to starting antidepressants, patients should have
laboratory testing to rule out:
IN Hypothyroidism
Anemia
Diabetes mellitus
Low estrogen levels
0
of 2.5
Question 53. Question
:
What impact does developmental variation in renal function
has on prescribing for infants and children?
Lower doses of renally excreted drugs may be
prescribed to infants younger than six months
Higher doses of water-soluble drugs may need
to be prescribed due to increased renal excretion
Renal excretion rates have no impact on
prescribing
Parents need to be instructed on whether drugs
are renally excreted or not
Question 54. Question
:
All diabetic patients with hyperlipidemia should be treated
with:
3-hydroxy-3-methylglutaryl coenzyme A
(HMG-CoA) reductase inhibitors
Fibric acid derivatives
Nicotinic acid
Colestipol
Question 55. Question
:
Treatment failure in patients with PUD associated with H.
pylori may be due to:
Antimicrobial resistance
Ineffective antacid
Overuse of PPIs
All of the above
Question 56. Question
:
To improve positive outcomes when prescribing for the
elderly, the NP should:
Assess cognitive functioning in the elder
Encourage the patient to take a weekly “drug
holiday” to keep drug costs down
Encourage the patient to cut drugs in half
with a knife to lower costs
All of the above options are
Question 57. Question
:
Erik presents with a golden-crusted lesion at the site of an
insect bite consistent with impetigo. His parents have limited finances and
request the least expensive treatment. Which medication would be the best
choice for treatment?
Mupirocin (Bactroban)
Bacitracin and polymixin B (generic double
antibiotic ointment)
Retapamulin (Altabax)
Oral cephalexin (Keflex)
Question 58. Question
:
Nonselective beta blockers and alcohol create serious drug
interactions with insulin because they:
Increase blood glucose levels.
Produce unexplained diaphoresis.
Interfere with the ability of the body to
metabolize glucose.
Mask the signs and symptoms of altered glucose
levels.
Question 59. Question
:
Infants and young children are at higher risk of ADRs due
to:
Immature renal function in school-age children
Lack of safety and efficacy studies in the
pediatric population
Children’s skin being thicker than adults,
requiring higher dosages of topical medication
Infant boys having a higher proportion of
muscle mass, leading to a higher volume of distribution
Question 60. Question
:
Warfarin resistance may be seen in patients with VCORC1
mutation, leading to:
Toxic levels of warfarin building up
Decreased response to warfarin
Increased risk for significant drug
interactions with warfarin
Less risk of drug interactions with warfarin
Question 61. Question
:
Jose is a twelve-year-old overweight child with a total cholesterol
level of 180 mg/dL and LDL of 125 mg/dL. Along with diet education and
recommending increased physical activity, a treatment plan for Jose would
include ____ with a reevaluation in six months.
statins
niacin
sterols
bile acid-binding resins
Question 62. Question
:
A potentially life-threatening adverse response to ACE
inhibitors is angioedema. Which of the following statements is true about this
adverse response?
Swelling of the tongue and hoarseness are the
most common symptoms.
It appears to be related to a decrease in
aldosterone production.
The presence of a dry, hacky cough indicates a
high risk for this adverse response.
Because it takes time to build up a blood
level, it occurs after being on the drug for about one week.
Question 63. Question
:
Amber is a twenty-four-year-old who has had migraines for
ten years. She reports a migraine on average of once a month. The migraines are
effectively aborted with naratriptan (Amerge). When refilling Amber’s
naratriptan education would include which of the following?
Naratriptan will interact with
antidepressants, including selective serotonin reuptake inhibitors and St
John’s Wort, and she should inform any providers she sees that she has
migraines.
Continue to monitor her headaches; if the
migraine is consistently happening around her menses, then there is preventive
therapy available.
Pregnancy is contraindicated when taking a
triptan.
All the given options are .
Question 64. Question
:
One of the main drug classes used to treat acute pain is
NSAIDs. They are used due to which of the following reasons?
They have less risk for liver damage than
acetaminophen.
Inflammation is a common cause of acute pain.
They have minimal GI irritation.
Regulation of blood flow to the kidney is not
affected by these drugs.
Question 65. Question
:
A patient has been prescribed silver sulfadiazine
(Silvadene) cream to treat burns on his or her leg. Normal adverse effects of
silver sulfadiazine cream include:
Transient leukopenia on days two to four that
should resolve
Worsening of burn symptoms briefly before
resolution
A red, scaly rash that will resolve with
continued use
Hypercalcemia
Question 66. Question
:
Sulfonylureas may be added to a treatment regimen for type
II diabetics when lifestyle modifications and metformin are insufficient to
achieve target glucose levels. Sulfonylureas have been moved to Step 2 therapy
because they:
Increase endogenous insulin secretion.
Have a significant risk for hypoglycemia.
Address the insulin resistance found in type
II diabetics.
Improve insulin binding to receptors.
Question 67. Question
:
Narcotics are exogenous opiates. They act by ______.
inhibiting pain transmission in the spinal
cord
attaching to receptors in the afferent neuron
to inhibit the release of substance P
blocking neurotransmitters in the midbrain
increasing beta-lipoprotein excretion from the
pituitary
Question 68. Question
:
Patients who are on or who will be starting chronic
corticosteroid therapy need monitoring of __________.
serum glucose
stool culture
folate levels
vitamin B12
Question 69. Question
:
Henry presents to clinic with a significantly swollen,
painful great toe and is diagnosed with gout. Of the following, which would be
the best treatment for Henry?
High-dose colchicines
Low-dose colchicines
High-dose aspirin
Acetaminophen with codeine
Question 70. Question
:
Jaycee has been on escitalopram (Lexapro) for a year and is
willing to try tapering off of the selective-serotonin reuptake inhibitors.
What is the initial dosage adjustment when starting a taper off
antidepressants?
Change the dose to every other day dosing for
a week.
Reduce the dose by 50% for three to four days.
Reduce the dose by 50% every other day.
Escitalopram (Lexapro) can be stopped abruptly
due to its long half-life.
Question 71. Question
:
Christy has exercise and mild persistent asthma and is
prescribed two puffs of albuterol fifteen minutes before exercise and as needed
for wheezing. One puff per day of beclomethasone (Qvar) is also prescribed.
Teaching regarding her inhalers includes which one of the following?
She should use one to two puffs of albuterol
per day to prevent an attack, with no more than eight puffs per day.
Beclomethasone needs to be used every day to
treat her asthma.
She should report any systemic side effects
she is experiencing, such as weight gain.
She should use the albuterol MDI immediately
after her corticosteroid MDI to facilitate bronchodilation.
Question 72. Question
:
Asthma exacerbations at home are managed by the patient by:
Increasing the frequency of beta 2 agonists
and contacting his or her provider
Doubling inhaled corticosteroid dose
Increasing the frequency of beta 2 agonists
Starting montelukast (Singulair)
Question 73. Question
:
A woman with an intact uterus should not be prescribed:
Estrogen/progesterone combination
Intramuscular (IM) medroxyprogesterone (Depo
Provera)
Estrogen alone
Androgens
Question 74. Question
:
The drug recommended as primary prevention of osteoporosis
in women over seventy years old is:
Alendronate (Fosamax)
Ibandronate (Boniva)
Calcium carbonate
Raloxifene (Evista)
Question 75. Question
:
Patient education when prescribing the vitamin D3 derivative
calcipotriene for psoriasis includes:
Applying calcipotriene thickly to affected
psoriatic areas two to three times a day
Applying a maximum of 100 grams of
calcipotriene per week
Not using calcipotriene in combination with
its topical corticosteroids
Augmenting calcipotriene with the use of
coal-tar products
Question 76. Question
:
Both ACE inhibitors and some angiotensin-II receptor
blockers have been approved in treating:
Hypertension in diabetic patients
Diabetic nephropathy
Both A and B
Neither A nor B
Question 77. Question
:
Scott is presenting for follow-up on his lipid panel. He had
elevated total cholesterol, elevated triglycerides, and an LDL of 122 mg/dL. He
has already implemented diet changes and increased physical activity. He has
mildly elevated liver studies. An appropriate next step for therapy would be:
Atorvastatin (Lipitor)
Niacin (Niaspan)
Simvastatin and ezetimibe (Vytorin)
Gemfibrozil (Lopid)
Question 78. Question
:
Hypoglycemia can result from the action of either insulin or
an oral hypoglycemic. Signs and symptoms of hypoglycemia include:
“Fruity” breath odor and rapid respiration
Diarrhea, abdominal pain, weight loss, and
hypertension
Dizziness, confusion, diaphoresis, and
tachycardia
Easy bruising, palpitations, cardiac
dysrhythmias, and coma
Question 79. Question
:
Incorporating IT into a patient encounter takes skill and
tact. During the encounter, the provider can make the patient more comfortable
with the IT the provider is using by:
Turning the screen around so the patient can
see material being recorded
Not placing the computer screen between the
provider and the patient
Both A and B
Neither A nor B
Question 80. Question
:
Which one of the below-given instructions can be followed
for applying a topical antibiotic or antiviral ointment?
Apply thickly to the infected area, spreading
the medication well past the borders of the infection
If the rash worsens, apply a thicker layer of
medication to settle down the infection
Wash hands before and after application of
topical antimicrobials
None of the above
Question 81. Question
:
Sadie is a ninety-year-old patient who requires a new
prescription. What changes in drug distribution with aging would influence prescribing
for Sadie?
Increased volume of distribution
Decreased lipid solubility
Decreased plasma proteins
Increased muscle-to-fat ratio
Question 82. Question
:
First-line therapy for treating topical fungal infections
such as tinea corporis (ringworm) or tinea pedis (athlete’s foot) would be:
OTC topical azole (clotrimazole, miconazole)
Oral terbinafine
Oral griseofulvin microsize
Nystatin cream or ointment
Question 83. Question
:
Which of the following is true about procainamide and its
dosing schedule?
It produces bradycardia and should be used
cautiously in patients with cardiac conditions that a slower heart rate might
worsen.
GI adverse effects are common, so the drug
should be taken with food.
Adherence can be improved by using a
sustained-release formulation that can be given once daily.
Doses of this drug should be taken evenly
spaced around the clock to keep an even blood level.
Question 84. Question
:
A nurse practitioner would prescribe the liquid form of
ibuprofen for a six-year-old because:
Drugs given in liquid form are less irritating
to the stomach.
A six-year-old may have problems swallowing a
pill.
Liquid forms of medication eliminate the
concern for first-pass effect.
Liquid ibuprofen does not have to be dosed as
often as tablet form.
Question 85. Question
:
Kristine would like to start HRT to treat the significant
vasomotor symptoms she is experiencing during menopause. Education for a woman
considering hormone replacement would include:
Explaining that HRT is totally safe if used
for a short term
Telling her to ignore media hype regarding HRT
Discussing the advantages and risks of HRT
Encouraging the patient to use phytoestrogens
with the HRT
Question 86. Question
:
Xi, a fifty-four-year-old female, has a history of migraine
that does not respond well to OTC migraine medication. She is asking to try
Maxalt (rizatriptan) because it works well for her friend. Which of the
following actions would you take for appropriate decision making?
Prescribe Maxalt, but to monitor the use, only
give her four tablets with no refills.
Prescribe Maxalt and arrange to have her
observed in the clinic or urgent care with the first dose.
Explain that rizatriptan is not used for
postmenopausal migraines and recommend Fiorinal (aspirin and butalbital).
Prescribe sumatriptan (Imitrex) with the
explanation that it is the most effective triptan.
Question 87. Question
:
The elderly are at high risk of ADRs due to:
Having greater muscle mass than younger adults,
leading to higher volume of distribution
The extensive studies that have been conducted
on drug safety in this age group
The blood-brain barrier being less permeable,
requiring higher doses to achieve therapeutic effect
Age-related decrease in renal function
Question 88. Question
:
Jim presents with fungal infection of two of his toenails
(onychomycosis). Treatment for fungal infections of the nail includes:
Miconazole cream
Ketoconazole cream
Oral griseofulvin
Mupirocin cream
Question 89. Question
:
GLP-1 agonists:
Directly bind to a receptor in the pancreatic
beta cell.
Have been approved for monotherapy.
Speed gastric emptying to decrease appetite.
Can be given orally once daily.
Question 90. Question
:
Prophylactic use of bisphosphonates is recommended for
patients with early osteopenia related to long-term use of which of the
following drugs?
Selective estrogen-receptor modulators
Aspirin
Glucocorticoids
Calcium supplements
Question 91. Question
:
Inadequate vitamin D intake can contribute to the
development of osteoporosis by:
Increasing calcitonin production
Increasing calcium absorption from the
intestine
Altering calcium metabolism
Stimulating bone formation
Question 92. Question
:
Which of the following statements is true about age and
pain?
Use of drugs that depend heavily on the renal
system for excretion may require dosage adjustments in very young children.
Among the NSAIDs, indomethacin is the
preferred drug because of lower adverse effects profiles than other NSAIDs.
Older adults who have dementia probably do not
experience much pain due to loss of pain receptors in the brain.
Acetaminophen is especially useful in both
children and adults because it has no effect on platelets and has fewer adverse
effects than NSAIDs.
Question 93. Question
:
Selective estrogen receptor modifiers (SERMs) treat
osteoporosis by selectively:
Inhibiting magnesium resorption in the kidneys
Increasing calcium absorption from the
gastrointestinal (GI) tract
Acting on the bone to inhibit osteoblast
activity
Selectively acting on the estrogen receptors
in the bone
Question 94. Question
:
When a patient is on selective-serotonin reuptake
inhibitors:
The complete blood count must be monitored
every three to four months
Therapeutic blood levels must be monitored
every six months after a steady state is achieved.
Blood glucose must be monitored every three to
four months.
There is no laboratory monitoring required.
Question 95. Question
:
Patients whose total dose of prednisone exceed 1 gram will
most likely need a second prescription for _________.
metformin, a biguanide to prevent diabetes
omeprazole, a proton pump inhibitor to prevent
peptic ulcer disease
naproxen, an NSAID to treat joint pain
furosemide, a diuretic to treat fluid
retention
Question 96. Question
:
The ongoing monitoring of patients over the age sixty-five
years taking alendronate (Fosamax) or any other bisphosphonate is:
Annual dual energy X-ray absorptiometry (DEXA)
scans
Annual vitamin D level
Annual renal function evaluation
Electrolytes every three months
Question 97. Question
:
Anticholinergic agents, such as benztropine (Cogentin), may
be given with a phenothiazine to:
Reduce the chance of tardive dyskinesia.
Potentiate the effects of the drug.
Reduce the tolerance that tends to occur.
Increase CNS depression.
Question 98. Question
:
Diagnostic criteria for diabetes include:
Fasting blood glucose greater than 140 mg/dl
on two occasions
Postprandial blood glucose greater than 140
mg/dl
Fasting blood glucose 100 to 125 mg/dl on two
occasions
Symptoms of diabetes plus a casual blood
glucose greater than 200 mg/dl
Question 99. Question
:
Insulin preparations are divided into categories based on
onset, duration, and intensity of action following subcutaneous inject. Which
of the following insulin preparations has the shortest onset and duration of
action?
Insulin lispro
Insulin glulisine
Insulin glargine
Insulin detemir
Question 100. Cynthia
is taking valproate (Depakote) for seizures and would like to get pregnant.
What advice would you give her?
Valproate is safe during all trim
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